Hormone Specific Formulations™ Questions
Question: I noticed that your formulations have been reformulated in late 2012. Can you give me a summary of those changes?
Answer: As you have noticed, there have been significant updates to the Hormone Specific Formulations™ in the last few months. I wanted to give you a brief overview of those changes, and encourage you to use these upgraded formulations with the new dosage guidelines. We are seeing faster, more phenomenal and more lasting results.
The news dosage guideline is called Protocol 242™. This protocol uses 2 capsules per day during the Initiation Phase, 4 per day during the Restoration Phase, and 2 per day during the Maintenance Phase.
AdrenoMend™ and the other Hormone Specific Formulations™ have all been updated to use a 2-4-2 dosage protocol.. ThyroMend™, TestoGain™, EstroMend™, ProgestoMend™ have all been increased to 120 capsules per bottle. TestoQuench™ has been completely revised into two separate formulations that are each 120 capsules and use Protocol 242™. They each provide more gender specific control of the effects of excessive testosterone: TestoQuench™ for Women is more feminizing, while TestoQuench™ for Men provides more prostate protection. All formulations are now 100% vegetarian, including the capsules.
ThyroMend™ now has 120 capsules per bottle, instead of 90 capsules. The amount of herbs in each capsule has increased from 567 mg to 650 mg. There is now more Ascophyllum nodosum (Norwegian Kelp) to provide increased amounts of bioavialable iodine and additional protection of thyroid cells from damage due to increased oxidative stress that can occur with increased thyroid activity.
The iodine content is increased so ThyroMend™ can be effectively used in each phase of Protocol 242™. ThyroMend™ provides 133% of Daily Value for iodine in the Initiation and Maintenance dosages. The 400 mcg of iodine in the restoration phase is safely below 1,100 mcg, the dosage that has caused thyroid cell inflammation and damage in human studies.
TestoGain™ now has 120 capsules per bottle, instead of 90 capsules. Eurycoma longifolia (Tongkat Ali) was added to increase testosterone production and decrease the anti-testosterone effects of estrogen. Panax ginseng was also added to increase testosterone production. Ptychopetalum olacoides (Muira Puama) was added due to its ability to mimic testosterone and improve sexual function in both men and women, as well as decrease the anti-testosterone effects of cortisol.
Specific herbs have been highly concentrated in TestoGain™ to increase testosterone production and function and testosterone function in both men and women. For example, Eurycoma longifolia (Tongkat Ali) is a 100:1 concentration.
This formulation is much more potent. It should be used with Protocol 242™. TestoGain™ is best taken in the AM with food, or the dosage can split between AM and a noon dosage with food.
EstroMend™ now has 120 capsules per bottle, instead of 90 capsules. The amount of herbs in each capsule has increased from 540 mg to 745 mg. Centella asicatica (Gotu kola) was added for a number of reasons: To enhance memory function; to provide more anti-cancer properties, provide more antioxidant properties, and due to its microvascular protection (women have a higher risk of coronary microvascular disease).
EstroMend™ also has more Pueraria montana, Pueraria lobata & Trifolium pretense, providing a soy-free source of the isoflavones genistein and daidzein. There is also increased Humulus lupulus, to increase its therapeutic actions.
To accomplish these significant changes we removed the cranberry fruit extract to provide more room in the capsules. We also removed the soy to provide more room, and to make the formulation soy-free for people who want to avoid soy.
This is a more potent formulation, and works best with Protocol 242™. Taking EstroMend™ at night, with evening meal or a snack before bedtime, decreases night sweats and provides for a more restful, restorative sleep.
ProgestoMend™ now has 120 capsules per bottle, instead of 90 capsules. The amount of herbs in each capsule has increased from 700 mg to 720 mg. Ligusticum wallichii has been added due to its significant progestogenic activity (it is a potent and specific activator of the progesterone receptor). Researchers concluded that the phytoprogesterone properties may have “utility for treatment of conditions requiring progesterone action”. Viburnum opulus contains a number of constituents that mimic the antispasmodic, anti-inflammatory, and anxiolytic properties of progesterone.
This is a more potent formulation, and works best with Protocol 242™. Taking ProgestoMend™ at night, with evening meal or a snack before bedtime provides for a more restful, restorative sleep. Or, take in the daytime to decrease daytime anxiety.
TestoQuench™ for Women is more feminizing and specifically reformulated for women. In addition to decreasing excessive testosterone production and excessive testosterone symptoms, TestoQuench™ for Women promotes healthy production and function of estrogens and progesterone, the endogenous hormones that naturally control the actions of testosterone in women.
Paeonia lactiflora was added to decrease testosterone production by inhibiting the conversion of delta 4-androstenedione to testosterone in the ovary, while stimulating aromatase activity in the ovary to promote estradiol synthesis. Vitex-agnus castus was added due to its anti-androgen effect which decreases both LH and testosterone levels. Vitex agnus castus has been shown to increase progesterone levels and consequently support regulation of luteal function. Significant increases in plasma progesterone and total estrogens levels were shown, as were significant reduction in luteinizing and plasma prolactin hormones.
This potent, female specific formulation works best with Protocol 242™. Taking TestoQuench™ for Women at night, with evening meal or a snack before bedtime provides for a more restful, restorative sleep. Or, take in the daytime to decrease daytime anxiety.
TestoQuench™ for Men is more male specific with increased protective for prostate tissue and specifically reformulated for men. Piper cubeba has been added to provide additional inhibitions of 5 alpha-reductase II activity in the prostate, which is responsible for converting testosterone to its active form, dihydrotestosterone (DHT). Piper cubeba is also an androgen receptor (AR) antagonist, and down-regulated AR levels It suppressed cell growth and prostate-specific antigen (PSA) secretion stimulated by DHT. In addition to anti-androgenic properties, Piper cubeba also demonstrates anti-estrogenic and anti-inflammatory properties. These results support the use of Piper cubeba in phytotherapy against benign prostatic hyperplasia (BPH). Magnolia officinalis was added to provide additional protection of the prostate due to its ability to inhibit prostate tissue growth, and exhibit apoptotic (programmed cell death) and antiangiogenic effects.
TestoQuench™ for Men no longer has Foeniculum vulgare (fennel) or Trigonella foenum-graecum (Fenugreek), which are more specific for controlling female problems with excessive testosterone.
This potent, male specific formulation works well with Protocol 242™. Taking TestoQuench™ for Men at night, with evening meal or a snack before bedtime provides for a more restful, restorative sleep. Or, take in the daytime to decrease daytime anxiety.
AdrenoMend™ ingredients are unchanged but the dosage guidelines have been updated to use Protocol 242™. AdrenoMend™ is best taken in the AM with food, or the dosage can split between AM and a noon dosage with food.
Thank you for your question.
Joseph J Collins, RN, ND